THE PRESENT INVENTION PROVIDES MEANS AND METHODS FOR TREATING DIFFUSE LARGE B CELL LYMPHOMA (DLBCL). SPECIFICALLY, A BISPECIFIC CDI 9 X CD3 ANTIBODY WHICH ENGAGES T CELLS VIA ITS CD3 BINDING PORTION AND CONCOMITANTLY BINDS TO CDI9 ON THE SURFACE OF, IN PARTICULAR, LYMPHOMA CELLS VIA ITS CDI9 BINDING PORTION (I.E. A BISPECIFIC T CELL ENGAGER, “BITE”) IS ADMINISTERED FOR USE IN THE TREATMENT OF TUMOROUS MASS OF LYMOPHORETICULAR TISSUE AND/OR EXTRA NODAL LYMPHOMA CAUSED BY DLBCL IN A PATIENT.
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机译：本发明提供了用于治疗弥漫性大B细胞淋巴瘤（DLBCL）的装置和方法。特别是，一个双特异性CDI 9 X CD3抗体，通过其CD3结合部分与T细胞结合，并通过其CDI9结合部分（即B），特别是在淋巴瘤细胞的表面上与CDI9结合，即用于治疗DLBCL在患者中引起的淋巴性组织和/或结节外淋巴瘤的大量肿块的治疗。
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