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Pharmaceutical formulation of masked flavor that has a rapid onset of action

机译:具有起效作用的隐蔽香料的药物制剂

摘要

Pharmaceutical composition for oral administration, comprising a phosphodiesterase inhibitor selected from sildenafil citrate and at least one sugar alcohol selected from mannitol, sorbitol, xylitol, maltitol, lactitol, erythritol, treitol and Isomalt and sodium hydrogen carbonate as excipients Pharmaceuticals in the following proportions by weight: phosphodiesterase inhibitor: from 10 to 150 parts by weight in total; sugar alcohol: from 50 to 600 parts by weight in total; sodium hydrogen carbonate: from 2 to 100 parts by weight; and a pharmaceutically acceptable organic acid, in which the phosphodiesterase inhibitor and sugar alcohol are present as a powder mixture or as granules or as a powder mixture or as granules in a compacted tablet, and in which the alcohol of sugar includes or is Isomalt.
机译:口服给药的药物组合物,其包含选自柠檬酸西地那非的磷酸二酯酶抑制剂和选自甘露糖醇,山梨糖醇,木糖醇,麦芽糖醇,乳糖醇,赤藓糖醇,苏糖醇和异麦芽酮糖醇的至少一种糖醇和碳酸氢钠作为赋形剂,其含量按重量百分比如下: :磷酸二酯酶抑制剂:总计10至150重量份;糖醇:总计50至600重量份;碳酸氢钠:2至100重量份;药学上可接受的有机酸,其中磷酸二酯酶抑制剂和糖醇以粉末混合物或颗粒或粉末混合物或颗粒的形式存在于压制片剂中,并且糖醇包括或为异麦芽酮糖醇。

著录项

  • 公开/公告号ES2604484T3

    专利类型

  • 公开/公告日2017-03-07

    原文格式PDF

  • 申请/专利权人 PHARMATECH GMBH;

    申请/专利号ES20110736275T

  • 发明设计人 STECKEL HARTWIG;

    申请日2011-06-24

  • 分类号A61K9;A61K9/20;A61K47/02;A61K47/10;

  • 国家 ES

  • 入库时间 2022-08-21 13:35:27

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