N- 4- (quinolin-4-yloxy) cyclohexyl (methyl) (hetero) arylcarboxamides as androgen receptor antagonists, production and uses thereof as medicinal products

摘要

Compound of general formula (I) ** Formula ** in which R1 represents H, cyano, fluorine, chlorine or bromine; A represents 5-membered phenyl or heteroaryl, in which this phenyl or this 5-membered heteroaryl is optionally substituted by one, two or three substituents which are independently selected from each other: halogen, cyano, alkyl, haloalkyl, cycloalkyl, heterocyclyl, hydroxyl, alkoxy, fluoroalkoxy, cycloalkyloxy, amino, alkylamino, dialkylamino, cycloalkylamino, alkylcycloalkylamino, dicycloalkylamino, alkylcarbonylamino, cycloalkylcarbonylamino, alkyl-sulfanyl, cycloalkylsulfanyl, alkylsulfonyl, cycloalkylsyl, alkylsulfonylsyl, alkylsulfonyl, cycloalkylsyl, alkylsulfonyl, cycloalkylsyl, alkylsulfonyl, alkylsulfonyl, alkylsulfonyl, alkylsulfonyl, alkylsulfonylsyl, alkylsulfonyl, alkylsulfonyl, alkylsulfonyl, alkylsulfonyl, alkylsulfonyl, alkylsulfonyl, alkylsulfonyl, alkylsulfonyl, alkylsulfonyl, alkylsulfonyl, alkylsulfonyl, alkylsulfonyl, alkylsulfonyl, alkylsulfonyl, alkylsulfonyl, alkylsulfonyl terms alkoxycarbonyl-; n = 0, 1 or 2; or one of its salts, or its solvates or the solvates of its salts.