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Treatment of intervertebral disc degenaration using cells derived from umbilical cord and hydrogel tissue

机译:使用源自脐带和水凝胶组织的细胞治疗椎间盘退变

摘要

A hydrogel and a homogenous population isolated from cells obtained from human umbilical cord tissue, or a pharmaceutical composition comprising said hydrogel and homogeneous population isolated from cells, for use in the treatment of a disease or condition related to the degeneration of the intervertebral disc, in which the treatment comprises the improvement of the cellularity and architecture of a degenerated disc, in which the umbilical cord tissue is substantially free of blood and the isolated homogeneous population of cells is capable of self-renewal and expansion in culture , has the potential to differentiate and does not express CD117 or telomerase.
机译:从人脐带组织获得的细胞中分离的水凝胶和均质群体,或从细胞中分离的包含所述水凝胶和从细胞均质群体的药物组合物,用于治疗与椎间盘退变相关的疾病或病症。其中的治疗包括改善退变椎间盘的细胞性和结构,其中脐带组织基本无血,分离出的同质细胞群体能够自我更新和在培养中扩增,具有分化的潜力并且不表达CD117或端粒酶。

著录项

  • 公开/公告号ES2625041T3

    专利类型

  • 公开/公告日2017-07-18

    原文格式PDF

  • 申请/专利权人 DEPUY SYNTHES PRODUCTS INC.;

    申请/专利号ES20120725939T

  • 申请日2012-05-17

  • 分类号A61K38/18;A61K35/12;A61K35/48;A61K35/50;A61K35/51;A61K38/17;A61L27/22;A61L27/38;A61L27/52;A61L27/54;A61P29;C12N5/073;

  • 国家 ES

  • 入库时间 2022-08-21 13:35:15

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