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Modification of intrinsically disordered sequences for vaccine preparation

机译:修饰固有无序序列以制备疫苗

摘要

Antibody manufacturing process by introduction into a living non-human organism of a compound that contains one or more peptides that have a covalent and irreversible crosslinking or crosslinking between the same peptides or with a different peptide, the crosslinks are present in the secondary amine functions of one or more amino acids, covalently modified by xanlurenic acid, said peptides consist of a disordered sequence, which has been covalently modified, irreversible in the amino acid secondary amine functions.
机译:通过将包含一种或多种具有共价和不可逆交联或相同肽之间或与不同肽之间的交联的肽的化合物引入活的非人类生物体的抗体制造过程,所述交联存在于以下化合物的仲胺官能团中:一种或多种被黄二烯酸共价修饰的氨基酸,所述肽由无序序列组成,所述无序序列已被共价修饰,其氨基酸仲胺功能不可逆。

著录项

  • 公开/公告号ES2631731T3

    专利类型

  • 公开/公告日2017-09-04

    原文格式PDF

  • 申请/专利权人 MALINA HALINA;

    申请/专利号ES20080871347T

  • 发明设计人 MALINA HALINA;

    申请日2008-10-30

  • 分类号C07K14/47;A61K38;C07K7/06;C07K7/08;

  • 国家 ES

  • 入库时间 2022-08-21 13:35:12

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