ANTIBODY HAVING A T-CELL RECEPTOR-LIKE SPECIFICITY, YET HIGHER AFFINITY, AND THE USE OF SAME IN THE DETECTION AND TREATMENT OF CANCER, VIRAL INFECTION AND AUTOIMMUNE DISEASE

摘要

An isolated molecule which comprises an antibody specifically bindable with abinding affinity below 20 nanomolar, preferably below 10 nanomolar, to a humanmajor histocompatibility complex (MHC) class I being complexed with a HLA-restricted antigen and optionally further comprises an identifiable ortherapeutic moiety conjugated to the antibody.