Trail membrane-penetrating peptide-like mutant, method of preparing same, and use thereof

摘要

A TRAIL mutant is provided. The mutant is a truncation of an amino acid sequence of positions 114-281 of an extracellular portion of a wild-type TRAIL protein, wherein the amino acids at positions 114-121 of said truncation are mutated into eight arginines. The TRAIL mutant may be used to treat tumors.