首页> 外国专利> NEW 6-OXA-3,9, 15-TRIAZA-BICYCLO9.3.1 PENTADEC A- 1 ( 14), 1 1 ( 15), 12-TRIENE DERIVATIVES BASED COMPOUNDS AND THEIR APPLICATION AS LIGANDS OF ESSENTIAL METAL ION BASED MRI AND ⁵²MN BASED PET CONTRAST AGENTS

NEW 6-OXA-3,9, 15-TRIAZA-BICYCLO9.3.1 PENTADEC A- 1 ( 14), 1 1 ( 15), 12-TRIENE DERIVATIVES BASED COMPOUNDS AND THEIR APPLICATION AS LIGANDS OF ESSENTIAL METAL ION BASED MRI AND ⁵²MN BASED PET CONTRAST AGENTS

机译：新型6-OXA-3,9，15-三氮杂双环[9.3.1]五元共聚物A-1（14），1 1（15），12-三烯衍生物的化合物及其作为基本金属离子MRI的配体的应用和^{52 MN的PET造影剂}

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The one subject of the invention is the compounds of general formula (I), their isomers, their physiologically acceptable salts and/or Mn(ll), Fe(ll), Fe(lll), Co(ll) and Ni(ll) complexes and their application: where R₁| = - OH or -NR₃ R ₄amide functionality

机译：本发明的一个主题是通式（I）的化合物，其异构体，其生理上可接受的盐和/或Mn（II），Fe（II），Fe（III），Co（II）和Ni（II）配合物及其应用：其中R _{1 | =-OH或-NR _{3 R _{4 酰胺官能团}}}

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公开/公告号WO2017089849A1

专利类型
公开/公告日2017-06-01

原文格式PDF
申请/专利权人 DEBRECENI EGYETEM;
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申请/专利号WO2016HU00075
发明设计人 BOTÁR RICHÁRD;GARDA ZOLTÁN;FODOR TAMÁS;KÁLMÁN FERENC KRISZTIÁN;NAGY VIKTÓRIA;TIRCSÓ GYULA;TÓTH IMRE;
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申请日2016-11-25
分类号C07D498/08;A61K31/439;
国家 WO
入库时间 2022-08-21 13:30:58

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NEW 6-OXA-3,9, 15-TRIAZA-BICYCLO9.3.1 PENTADEC A- 1 ( 14), 1 1 ( 15), 12-TRIENE DERIVATIVES BASED COMPOUNDS AND THEIR APPLICATION AS LIGANDS OF ESSENTIAL METAL ION BASED MRI AND 52MN BASED PET CONTRAST AGENTS

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NEW 6-OXA-3,9, 15-TRIAZA-BICYCLO9.3.1 PENTADEC A- 1 ( 14), 1 1 ( 15), 12-TRIENE DERIVATIVES BASED COMPOUNDS AND THEIR APPLICATION AS LIGANDS OF ESSENTIAL METAL ION BASED MRI AND ⁵²MN BASED PET CONTRAST AGENTS