6-oxa-3,9,15-triaza-bicyclo9.3.1pentadeca-1(14),11(15),12-triene derivatives based compounds and their application as ligands of essential metal ion based MRI and ⁵²MN based PET contrast agents

摘要

The one subject of the invention is the compounds of general formula (I), their isomers, their physiologically acceptable salts and/or Mn(II), Fe(II), Fe(III), Co(II) and Ni(II) complexes and their application: where R₁|=—OH or —NR₃R₄ amide functionality.;