首页> 外国专利> PHOTOACTIVATABLE NANOPARTICLES FOR PHOTODYNAMIC APPLICATIONS, METHOD OF PREPARATION THEREOF, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND USE THEREOF

PHOTOACTIVATABLE NANOPARTICLES FOR PHOTODYNAMIC APPLICATIONS, METHOD OF PREPARATION THEREOF, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND USE THEREOF

机译：用于光动力学应用的可光活化纳米粒子，其制备方法，包含它们的药物成分及其用途

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摘要

The present invention relates to photoactivatable nanoparticles for photodynamic applications containing a photosensitizer, a (C₈ to C₂₂) fatty alcohol and a polymeric surfactant, preferably poly(ethylene oxide) monomethyl ether-block-poly(ε-caprolactone), whereas the size of the nanoparticle is in the range of from 1 to 1000 nm, and the core of the nanoparticle is solid at the temperature of 4 °C, and liquid at the temperature around 39 °C. The present invention further relates to a method of preparation of the photoactivatable nanoparticle, a pharmaceutical composition containing it, and use thereof.

机译：本发明涉及用于光动力应用的可光活化纳米粒子，其包含光敏剂，（C _{8 至C _{22 ）脂肪醇和聚合物表面活性剂，优选聚环氧乙烷单甲基醚-嵌段-聚（ε-己内酯），而纳米颗粒的尺寸在1至1000 nm范围内，并且纳米颗粒的核心在4°C的温度下为固体，液体温度约为39°C。本发明还涉及可光活化纳米颗粒的制备方法，包含该可光活化纳米颗粒的药物组合物及其用途。}} 展开▼

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公开/公告号WO2017148454A1

专利类型

公开/公告日2017-09-08

原文格式PDF

申请/专利权人 USTAV MAKROMOLEKULARNI CHEMIE AV CR V.V.I.;VYSOKA SKOLA CHEMICKO-TECHNOLOGICKA V PRAZE;
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申请/专利号WO2017CZ50008

发明设计人 HRUBY MARTIN;BREZANIOVA INGRID;KRAL VLADIMIR;
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申请日2017-02-24

分类号A61K41;A61K9/51;A61P35;

国家 WO

入库时间 2022-08-21 13:29:57

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