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METHODS FOR PREPARING 3'-AMINO-2',3'-DIDEOXYGUANOSINE BY USING NUCLEOSIDE PHOSPHORYLASES DERIVED FROM BACILLUS AND ADENOSINE DEAMINASE DERIVED FROM LACTOCOCCUS
METHODS FOR PREPARING 3'-AMINO-2',3'-DIDEOXYGUANOSINE BY USING NUCLEOSIDE PHOSPHORYLASES DERIVED FROM BACILLUS AND ADENOSINE DEAMINASE DERIVED FROM LACTOCOCCUS
The present invention relates to a method for preparing 3'-amino-2',3'-dideoxyguanosine using Bacillus stearothermophilus-derived nucleoside phosphorylases and Lactococcus lactis-derived adenosine deaminase. According to the method for preparing 3'-amino-2',3'-dideoxyguanosine of the present invention, 3'-amino-2,3'-dideoxyguanosine can be mass-produced efficiently and economically through high rate of enzymatic conversion and high purity of purifications.
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