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3'--2'3'- Methods for Preparing 3'-amino-2'3'-dideoxyguanosine by Using Nucleoside Phosphorylases Derived from Bacillus and Adenosine Deaminase Derived from Lactococcus
3'--2'3'- Methods for Preparing 3'-amino-2'3'-dideoxyguanosine by Using Nucleoside Phosphorylases Derived from Bacillus and Adenosine Deaminase Derived from Lactococcus
The present invention relates to a process for preparing 3'-amino-2 ', 3'-dideoxyguanosine using bacillus stearothermophilus-derived nucleoside phosphorylase and lactococcus lactis-derived adenosine deaminase. According to the method for producing 3'-amino-2 ', 3'-dideoxy guanosine according to the present invention, 3'-amino-2', 3'-dideoxy guanosine is converted and purified at high yield and high purity, 3'-amino-2 ', 3'-dideoxy guanosine can be mass-produced efficiently.
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