FRITILLARY FLOWER EXTRACTIVE PREPARATION METHOD

摘要

A fritillary flower extractive preparation method, comprising the following steps: cold-drying, grinding, sifting, and degreasing fritillary flowers, to obtain a filter cake; drying the filter cake, adding the filter cake to absolute ethyl alcohol for ultrasonic extraction, and performing filtering to obtain an extract solution and residue; performing supercritical carbon dioxide extraction on the residue to obtain an extract liquor, using ethanol water as entrainer; after mixing the extract liquor and the extracting solution, treating the mixture with a macroporous absorption resin, and then performing eluting by using water and ethyl alcohol in sequence, concentrating, and drying, to obtain a fritillary flower extractive. During the supercritical extraction, the extraction temperature is 52-55°C, the temperature of the first separation is 45-50°C, the temperature of the second separation is 35-40°C, the extraction pressure is 30-33 MPa, the flow rate of carbon dioxide is 10-20 L/h, the frequency of receiving a product is 45-50 min per time, and the extraction time is 3-4 h. The method features a high extraction speed, high extraction precision, and low production costs.