USE OF miR-3615, miR-5701, miR-5581-3p, miR-4792, AND miR-2467-5p WHICH ARE microRNAS FOR DIAGNOSIS OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE

摘要

The present invention provides a novel use of miR-3615, miR-5701, miR-5581-3p, miR-4792, and miR-2467-5p which are microRNAs for the diagnosis of chronic obstructive pulmonary diseases (COPD). The miR-3615, miR-5701, miR-5581-3p, miR-4792 and miR-2467-5p which are microRNAs of the present invention are selected as microRNAs having a negative correlation with related mRNAs through microRNA-mRNA integrating analysis, and thus have accurate diagnosis performances corresponding to the expression change of mRNA observed in actual COPD patients. The microRNAs of the present invention can be developed as a bio-marker for the diagnosis of COPD.;COPYRIGHT KIPO 2016