The present invention relates to a method and an apparatus for predicting pharmacodynamics drug-drug interactions by the commonness between drugs. The method for predicting pharmacodynamics drug-drug interactions by the commonness between drugs includes: a first step (S100) of establishing a drug-drug interaction network through pharmacodynamics drug-drug interaction data; a second step (S200) of calculating drug-drug interactions between at least two drugs on the network; and a third step (S300) of calculating a score for the calculated interaction between the at least two drugs.;COPYRIGHT KIPO 2017
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