Apolipoprotein D-GAL4 DROSOPHILA APOLIPOPROTEIN D-GAL4 DOUBLE MUTANTS AND THE MANUFACTURING METHOD OF THE SAME

摘要

The invention Drosophila ApolipoproteinD-GAL4 mutants and double mutants and relates to a method of manufacturing the same, more specifically to ApoD-GAL4 flies with mutant ApoD gene expression in tissue-specific double Drosophila which the fluorescent protein gene overexpression It relates to mutants and its manufacturing method. According to the present invention as described above, gene transfer for that can over-expression in a specific tissue expression system of GAL4 by using a system ApoD-specificApoD gene expression tissue produced by separating the promoter region of the gene from Drosophila genomic expression mutations and It provides a Drosophila double mutant comprising a fluorescent protein gene over-expression mutations at the same time, the fruit fly double mutants are useful animal model in ApoD related factor screening, as well as Drosophila gene function, degenerative brain disease related gene function in human studies it is available in. ;