Method for promoting nuclear maturation of canine oocytes

摘要

More particularly, the present invention relates to a method of in vitro maturation of dog eggs, and more specifically, to increase the activity of MPF (Maturation Promoting Factor) through inactivation of the Wee1B gene and to inhibit MI (metaphase) in the GV (germinal vesicle) To the step (I) of promoting the nuclear maturation of the oocyte.