首页> 外国专利> INJECTION COMPOSITION FOR PREVENTING OR TREATING OSTEOARTHRITIS, OR RELIEVING JOINT PAIN

INJECTION COMPOSITION FOR PREVENTING OR TREATING OSTEOARTHRITIS, OR RELIEVING JOINT PAIN

机译:预防或治疗骨关节炎或缓解关节痛的注射剂

摘要

The present invention relates to an injection composition for preventing or treating osteoarthritis, or reliving joint pain. The injection composition comprises microsphere having (1) piroxicam or a pharmaceutically allowable salt thereof, and (2) a carrier for a glenoid cavity administration drug including: a core polymer in which the piroxicam or the pharmaceutically allowable salt thereof is sealed; a cationic polymer of which one end is mixed with the core polymer in a non-shared manner, and the other end provides a positive charge on the surface of a carrier; and a film polymer covering part or the entire surface of the core polymer. According to the present invention, the injection composition can improve retention of piroxicam components in the glenoid cavity, and can sustain effects of preventing or treating osteoarthritis, or reliving joint pain for a long time after single dose.;COPYRIGHT KIPO 2017
机译:本发明涉及用于预防或治疗骨关节炎或减轻关节痛的注射组合物。该注射剂组合物包含具有(1)吡罗昔康或其药学上允许的盐和(2)关节盂腔给药药物的载体的微球,所述载体包括:密封有吡罗昔康或其药学上允许的盐的核聚合物;阳离子聚合物,其一端与核聚合物以非共享方式混合,另一端在载体表面上提供正电荷;膜聚合物覆盖芯聚合物的一部分或整个表面。根据本发明,所述注射组合物可以改善吡罗昔康成分在盂腔中的保留,并且可以在单次给药后长时间维持预防或治疗骨关节炎或减轻关节疼痛的效果。COPYRIGHTKIPO 2017

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