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NOVEL METHOD FOR PRODUCING CITALOPRAM AND ESCITALOPRAM
NOVEL METHOD FOR PRODUCING CITALOPRAM AND ESCITALOPRAM
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机译:制作图文并茂的新方法
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摘要
The present invention provides a production method comprising the steps of: producing a compound of chemical formula 2 by esterifying a compound of chemical formula 3 with a compound of chemical formula 4; and synthesizing citalopram by cyclizing the compound of chemical formula 2 under the presence of a base. In the formulas, X is a leaving group, and Y is selected from H, NO_2, CF_3, CN, or Cl. According to the present invention, citalopram and escitalopram are produced at high purity and high yield.;COPYRIGHT KIPO 2017
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