Application of Large-Dose Glycerinum in Freeze-Thawing Tolerable Lipid Emulsion

摘要

The present invention relates to a fat emulsion which belongs to a fat emulsion region and is able to withstand the application of high concentration glycerin to a fat emulsion which can withstand freezing and thawing and a kind of freeze-thaw. The high-concentration glycerin refers to glycerin having a content of ≥3 w / v% in the emulsion ingredients. The maximum capacity is 50 w / v% of the total amount of the emulsion ingredients. If the total amount of oil solution in the emulsion ingredients is 2% -30w / v%, the glycerin capacity is more than 1/3 of the oil amount in the emulsion. The present invention may also add drug-containing drug emulsions. Compared to the existing technology, the fat emulsion which can withstand the freezing and thawing provided by the present invention is able to withstand the freezing and thawing of the low temperature, so that the stability of the medicine caused by the change of the temperature condition during transportation, storage and use of the product And can reduce the cost of drug use by lowering the requirements of transportation and storage conditions.