Methods for identifying and filtering of false somatic variants caused by laboratory vector contamination

摘要

The present invention relates to alkali ranking analysis, about the method for sympathizing with vector pollution. The present inventors suggest sympathizing with using Vecux the vector of above-mentioned vector to polluteVecuens is not only more preferable than pervious method, but also to the sympathy problem of vector, can shorten and calculate the time. Technology is impossible before Vecual also can detecte out, and the position of contaminated people can detecte out most falsevils. In addition, this hair name is by according to the shared information of Vecuex, suitable for the hair county vector of mammal, including mouse gene and preed mrNA(cDNA), it include a variety of external contamination sources. As a result, Vecual will provide new method for quality control to external contamination, the degree of belief (reliabilit) of the low frequency variability signals (cris) in NGS sequence datas is improved.