Genetically modified bacterial strain for the detection of estrogenic compounds and detection method for estrogenic compounds using the strain

摘要

The present invention relates to a mutant bacterial strain for the detection of an estrogenic compound and a method for detecting an estrogenic compound using the same, and more particularly, to a method for detecting an estrogenic compound using a co-regulatory factor that interacts with a ligand binding site (ER LBD) A plasmid A containing a nucleotide sequence in which a coding gene is joined to a gene encoding a lambda C protein; And a gene encoding a ligand binding site (ER LBD) of an estrogen receptor is transformed with a plasmid B conjugated with a gene encoding an αNTD protein, a bacterial strain having the ability to detect an estrogenic compound and estrogen The present invention relates to a method for detecting a compound. According to the present invention there is provided a gene mutant bacteria for the detection of an estrogenic compound having a very short detection time with low cost and labor by an environmentally friendly, relatively simple process because it is based on human estrogen receptor protein, A method for detecting an estrogenic compound using the same can be provided.;