Pharmaceutical composition for the prevention and treatment of neurodegenerative disease comprising Coriandrum sativum L. as an active ingredient

摘要

The present invention relates to a process for the preparation of coriandrumsativumL. ; The present invention relates to a composition for prevention and treatment of degenerative brain diseases, which comprises fractions prepared from extracts of Nrf2 and CS as an active ingredient. More particularly, And inhibit the overproduction of ROS, resulting in an increase in MPP ⁺ toxicity Since the fractions prepared by protecting PC12 cells, BV2 cells, and midbrain dopamine cells and fractionating the high-water extract with an organic solvent inhibit acetylcholine esterase and significantly increase cell survival rate, degenerative brain diseases Can be easily used for prevention and treatment.