MTBK_20640 Vaccine composition for tuberculosis containing MTBK_20640 protein

摘要

The present invention relates to tuberculosis treatment or prevention a pharmaceutical composition comprising a vaccine composition and MTBK_20640 protein for tuberculosis prevention, including MTBK_20640 protein. MTBK_20640 protein according to the invention exhibit a high IFN-γ producing ability in the spleen and lung in animal models induced by infection by M. tuberculosis and kept the memory screen in the Quick acquired protective immunity form and T cells by giving an effective prevention of tuberculosis is. In particular, it leads to the production of the recent multi-functional T cells, known to be important in the prevention of tuberculosis. Also available, even in the treatment of Tuberculosis recurrence or re-infection of the high recurrence rate, and highly pathogenic tuberculosis to be useful in improving the treatment efficiency. ;