a fabricating method of nanofibers as a nitric oxide storage and delivery scaffold and the nanofibers as a nitric oxide storage and delivery scaffoldfabricated thereby

摘要

The present invention relates to a method for manufacturing nanofibers capable of storing and transferring nitric oxide, and nanofibers manufactured thereby. The present invention comprises: a filling step of filling a first material with nitric oxide; a synthesis step of synthesizing a second material having a functional group capable of covalently bonding to the first material; a sol-gel reaction step of conducting the sol-gel reaction of the first material filled with nitric oxide with the second material so as to manufacture a gel; and an electrospinning step of electrospinning the gel so as to manufacture nanofibers. According to the present invention, it is possible to manufacture nanofibers by filling a material with nitric oxide and then using a sol-gel reaction and an electrospinning process, and to variously control emission characteristics of the nitric oxide by controlling the kind and concentration of aminoalcoxysilane and the weight ratio of a polymer solution.;COPYRIGHT KIPO 2014