METHOD FOR MANUFACTURING SUBSTANCE CONTAINING NOBILETIN AND TANGERETIN DERIVED FROM CITRUS FRUITS AND NOBILETIN- AND TANGERETIN-CONTAINING SUBSTANCE OBTAINED THEREBY

摘要

It is an object of the present invention to provide a method for producing fractions containing high concentrations of nobiletin and tangeretin which are excellent in safety, economy and industrialization. (1-1) A process for producing a hydrothermally treated product by treating citrus fruits with hot water; (1-2) a step of drying the hydrothermally treated product to obtain a dried product; (1-3) a step of obtaining the nobiletin and the tannate solubilizing substance by treating the dried product with a solvent which is soluble in nobiletin and tangeretin; (3) a step of concentrating and / or drying the nobiletin and the tannate solubilizing substance to obtain a nobiletin and a tannate concentrate; And (4) a step of treating the nobiletin and tangeretine concentrate with a dilute alkali to obtain nobiletin and a tangeretin-containing substance as an insoluble component, and a process for producing nobiletin and tangeretine- It is solved by high content of nobiletin and tangeretin.