Method to prepare nontoxic fluorescent nano-particles coated hydrophilic silicon containing polymers complexed with Lanthanide

摘要

The present invention relates to a method for producing a nanoparticle, comprising the steps of: (a) synthesizing a copolymer comprising a silicone compound and a water-soluble polymer; (b) preparing a core material of nanoparticles; (c) preparing a lanthanide metal complex; The mixture obtained in step (a) and step (c) is mixed at a ratio of 1: 0.2 to 1: 0.5 by mass and the mixture is mixed with the core material obtained in step (b) : 1, and (e) fluorescent nanoparticles obtained by heat-cross-linking the particles obtained in (d), and a method for producing the same.;