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DNA Method for manufacturing transgenic Caenorhabditis elegans with DNA methyltransferase and use thereof

机译：DNA甲基转移酶生产转基因秀丽隐杆线虫的DNA方法及其用途

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摘要

The present invention relates to a method for screening for the expression of Dnmt3a (DNA methyltransferase 3a)CaenorhabditisElegans) And a method for producing the same. According to the present invention, it is possible to identify specific mechanisms and related factors of DNA methylation by Dnmt3a, identify important genes that regulate the life span of nymphs, and also provide animal models for drug screening for DNA methylation-. /RTI ;

机译：本发明涉及一种筛选Dnmt3a（DNA甲基转移酶3a）Caenorhabditis Elegans 的表达的方法及其生产方法。根据本发明，有可能通过Dnmt3a鉴定DNA甲基化的具体机理和相关因素，鉴定调节若虫寿命的重要基因，并提供用于DNA甲基化的药物筛选的动物模型。 展开▼

著录项

公开/公告号KR101759785B1

专利类型

公开/公告日2017-07-20

原文格式PDF

申请/专利权人 포항공과대학교 산학협력단;
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申请/专利号KR20150104475

发明设计人 이승재;남홍길;노태영;무랏아르탄;김유나;
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申请日2015-07-23

分类号A01K67/027;

国家 KR

入库时间 2022-08-21 13:25:07

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3. DNA Method for manufacturing transgenic Caenorhabditis elegans with DNA methyltransferase and use thereof [P] . 韩国专利： KR20170011602A . 2017-02-02

机译： DNA甲基转移酶生产转基因秀丽隐杆线虫的DNA方法及其用途

4. Method for manufacturing transgenic caenorhabditis elegans with DNA methyltransferase and use thereof [P] . 美国专利： US9681648B2 . 2017-06-20

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5. Method for Manufacturing Transgenic Caenorhabditis Elegans with DNA Methyltransferase and Use Thereof [P] . 美国专利： US2017020116A1 . 2017-01-26

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10. Caenorhabditis elegans Protein Arginine Methyltransferase PRMT-5 Negatively Regulates DNA Damage-Induced Apoptosis [O] . Yang, Mei, Sun, Jianwei, Sun, Xiaojuan, 2009

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