IL-1 Composition comprising Morifolium extract asan effective component for preventing and treatingarthritis

摘要

The present invention relates to a composition for the prevention or amelioration of arthritis due to IL-1β which includes the reconstituted tobacco extract as an active ingredient. The composition for preventing or improving arthritis due to IL-1β according to the invention may be one comprising a reconstituted tobacco extract as an active ingredient. If it depends a reconstituted tobacco extract according to the present invention to a composition for osteoarthritis prevention or improvement by the IL-1β which includes as the active ingredient, by inhibiting the MAPK family and activity of NF-κB, iNOS, NO, COX-2, PGE ₂ and it can suppress the expression of MMP to protect the substrate and to suppress the inflammatory response.;