RNABIOMARKER MICRO RNA FOR PREDICTING PROGNOSIS OF HEAD AND NECK SQUAMOUS CELL CARCINOMA

摘要

The present invention relates to a microRNA (hereinafter referred to as 'miRNA') which can be used as a biomarker for predicting the prognosis of head and neck cancer. Specifically, the miRNA is miR-206, miR-127-5p, miR-432 -15p, miR-409-5p, miR-145-3p, miR-497-5p, miR-195-5p, miR-150-5p, miR-140-3p, miR-214-3p, miR-125b-5p , miR-200b-3p, miR-200c-3p, miR-141-3p, miR-200a-5p, miR-200a-3p, miR-200b-5p, 17p, miR-20a-5p, miR-92a-3p, miR-93b-3p, miR-93-5p, miR-17-3p, , miR-324-3p, miR-193a-5p, miR-149-5p, miR-1307-3p, miR-107, miR-103a-3p, miR-221-3p, miR222, The aim of this study was to determine the prognosis and prognosis of head and neck carcinoma subtypes according to the expression level of miRNAs selected from the group consisting of -24-3p, miR-27b-5p, miR-27b-3p and miR-23b-3p. The present invention is expected to provide rapid and more accurate prediction of the prognosis of head and neck cancer through the expression level of miRNA and it is expected to be effective in predicting effective prognosis of head and neck cancer.