PHARMACEUTICAL COMPOSITION COMPRISING THE ROOT EXTRACT OF BLACK PLATYCODON GRANDIFLORUM AS AN EFFECTIVE COMPONENT FOR PREVENTION OR TREATMENT OF HEAVY METAL TOXICITY RELATED DISEASES AND FUNCTIONAL FOOD COMPRISING THE SAME

摘要

The present invention relates to a pharmaceutical composition and a health functional food for the prevention and treatment of heavy metal toxicity related diseases containing an extract of black long hot water as an active ingredient. More specifically, the present invention relates to a pharmaceutical composition, Which is obtained by heating and drying at 70 to 75 캜 for 10 days or more without adding water as an active ingredient, to a pharmaceutical composition and a health functional food for prevention and treatment of heavy metal toxicity related diseases. The composition for preventing and treating heavy metal toxicity related diseases of the present invention and the blackrodden hot-water extract as an active ingredient of the health functional food, the ethyl acetate fraction, the butanol fraction and the water residue thereof, Likewise, it is prepared by hot water extraction of the black dorado produced by heating and drying in a sealed container, followed by sequential fractionation using hexane, ethyl acetate and butanol. The ethyl acetate fraction, the butanol fraction and the water residue, These fractions effectively inhibit the death of human lung cells caused by cadmium and copper, and are an extremely useful invention in the pharmaceutical industry and the food industry because they have excellent effects that can be used for the prevention and treatment of various diseases caused by heavy metal exposure.