The composition comprising the specific extract or the purified fraction isolated from Salvia pleia R. Br. as an active ingredient for preventing or treating respiratory inflammatory disease

摘要

The present invention relates to a composition for preventing or treating respiratory inflammation containing the purified fraction of blisters cabbages 10 to 60% ethanol or the extract soluble in ethanol or separated therefrom as an active ingredient. Inhibiting 5-lipoxygenase (5-lipoxygenase, 5-LO) targeting blisters cabbage extract with basophil white blood cells according to the invention act experiment (flow KOTRA two yen inhibiting expression), LPS-induced BALB / c mice using a model inhibition experiment for the respiratory acute inflammation; BALB / c can be effectively used in the prevention or treatment of, by and safety through the inhibition of allergic asthma using a mouse model active experiment with respect to the respiratory tract inflammatory diseases excellent than the extract described in the prior literature, and confirmed strong therapeutic efficacy of respiratory inflammatory diseases .;