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METHOD OF PRODUCING NANOCAPSULES OF CEPHALOSPORIN PREPARATIONS IN INTERFERON
METHOD OF PRODUCING NANOCAPSULES OF CEPHALOSPORIN PREPARATIONS IN INTERFERON
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机译:干扰素中头孢氨苄制剂纳米胶囊的制备方法
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摘要
FIELD: medicine.;SUBSTANCE: invention relates to medicine and consists in method of producing microcapsules of cephalosporin preparations, in which envelope is interferon, core is preparations of cephalosporins. During method implementation cephalosporin preparations and E472c as surfactant are added to aqueous solution of interferon, obtained mixture is mixed in magnetic stirrer until dissolving of mixture components to produce transparent solution, then slowly chloroform is added by drops, obtained suspension is filtered, washed with chloroform and dried, wherein ratio shell:core is 3:1.;EFFECT: technical result consists in simplifying and accelerating of production of nanocapsules, as well as increase of mass output.;1 cl, 1 dwg, 9 ex
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机译:头孢菌素制剂微胶囊的制备方法技术领域本发明涉及药物,涉及一种头孢菌素制剂微胶囊的制备方法,其中包膜为干扰素,核心为头孢菌素制剂。在方法实施过程中,将头孢菌素制剂和E472c作为表面活性剂添加到干扰素水溶液中,将得到的混合物在磁力搅拌器中混合直至溶解混合物成分以产生透明溶液,然后缓慢滴加氯仿,过滤得到的悬浮液,用氯仿洗涤干燥并干燥,其中壳:芯比为3∶1。效果:技术结果在于简化和加速纳米胶囊的生产以及增加产量。1 cl,1 dwg,9 ex
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