METHOD FOR OBTAINING NANOCAPSULES OF MEDICATIONS OF PENICILLIN GOUP IN SODIUM ALGINATE

摘要

FIELD: medicine, pharmaceutics.;SUBSTANCE: invention relates to method for obtaining nanocapsules of medications of penicillin group, selected from ampicillin, sodium salt of benzylpenicillin or amoxicillin. The claimed method is characterised by the fact that 0.01 g of preparation E472c is added to 0.5 g of sodium algenate in petroleum ether as surface active substance, 0.5 g of antibiotic powder is added to obtained suspension in small portions, with the following addition of 5 ml of chloroform, obtained suspension of nanocapsules is filtered and dried.;EFFECT: invention ensures simplification and acceleration of process of obtaining nanocapsules of penicillin group medications, as well as increase of their output by weight.;3 dwg, 7 ex