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NEW TRIAZINE SUBSTANCE FOR USE IN THE TREATMENT OF CANCER, SPECIFICALLY IN THE TREATMENT OF NON-SMALL CELL CANCER, AND PHARMACEUTICAL COMPOSITION COMPRISING SAID SUBSTANCE
NEW TRIAZINE SUBSTANCE FOR USE IN THE TREATMENT OF CANCER, SPECIFICALLY IN THE TREATMENT OF NON-SMALL CELL CANCER, AND PHARMACEUTICAL COMPOSITION COMPRISING SAID SUBSTANCE
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机译:新的三嗪类物质,用于治疗癌症,特别是用于治疗非小细胞癌以及包含所述物质的药物成分
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摘要
Substance of formula (I) for use as a medicamentwherein A is a [-(CH2)n-] spacer, n being an integer comprised between 1 and 3, preferably between 1 and 2 ; Xm are m substituents, m being an integer comprised between 1 and 3, wherein X is chosen among Cl, Br, OCH3 or SCH3; and R1, R2, R3 and R4 are chosen among hydrogen atoms or C1-C3 alkyl groups. This substance has an anti-proliferative action on tumor cells and may advantageously be for use in the treatment of non-small cell cancer, preferably for use in the treatment of non-small cell squamous carcinoma, and more preferably for use in the treatment of non-small cell lung cancer.
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机译:用作药物的式(I)物质 <图像文件=“ IMGA0001.GIF” he =“ 78” id =“ ia01” imgContent =“ chem” imgFormat =“ GIF” wi =“ 117” /> Chemistry>其中A为[-(CH 2 Sub>)n-]间隔基,n为1至3,优选1至2的整数; X m Sub>为m个取代基,m为1至3的整数,其中X选自Cl,Br,OCH 3 Sub>或SCH 3 Sub >;和R 1 Sub>,R 2 Sub>,R 3 Sub>和R 4 Sub>选自氢原子或C 1 Sub> -C 3 Sub>烷基。该物质对肿瘤细胞具有抗增殖作用,可有利地用于治疗非小细胞癌,优选用于治疗非小细胞鳞癌,更优选用于治疗非小细胞鳞癌。非小细胞肺癌。
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