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SYSTEMS AND METHODS FOR ENRICHING A BACTERIAL STRAIN FROM A TARGET BACTERIAL SYSTEM
SYSTEMS AND METHODS FOR ENRICHING A BACTERIAL STRAIN FROM A TARGET BACTERIAL SYSTEM
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机译:用于从目标细菌系统富集细菌菌株的系统和方法
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摘要
The present invention is a method of enriching at least one bacterial species from a target bacterial system, including: culturing the target bacterial ecosystem in a culture media in a single-stage chemostat under the following conditions: (i) a system retention time of about 5 to about 290 hours, (ii) a temperature of about 37° C., (iii) a pH of about 6.8 to 7, and (iv) maintenance of Establish anaerobic conditions to the chemostat for a time sufficient to enrich the at least one bacterial species; where the culture media comprises a prepared starch substrate, and where the target bacterial system is a fecal derived sample obtained from a patient that has not been treated with an antibiotic for at least 6 months.
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