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TWO CONOTOXIN PEPTIDES, PREPARATION METHODS THEREFOR, AND APPLICATIONS THEREOF
TWO CONOTOXIN PEPTIDES, PREPARATION METHODS THEREFOR, AND APPLICATIONS THEREOF
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机译:两种牙龈毒素肽,其制备方法及其应用
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摘要
Provided are two novel conotoxin peptides, namely ω-CPTx-btl1 and ω-CPTx-btl2, amino acid sequences thereof being shown as SEQ ID NO: 1 or 2 respectively. Also provided are polynucleotides coding these two peptides, constructs, expression vectors and transformed cells containing the polynucleotides, and preparation methods for the two peptides. The conotoxin peptides can be applied to treatment of calcium ion channel-related diseases.
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机译:提供了两种新型的芋螺毒素肽,即ω-CPTx-btl1和ω-CPTx-btl2,其氨基酸序列分别示为SEQ ID NO:1或2。还提供了编码这两种肽的多核苷酸,包含该多核苷酸的构建体,表达载体和转化细胞,以及这两种肽的制备方法。芋螺毒素肽可用于治疗钙离子通道相关疾病。
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