首页> 外国专利> USE OF ANTIBIOTICS WITH SPECIFIC THERAPEUTIC ACTIVITIES COMBINED WITH THE SIMULTANEOUS USE OF LACTOBACILLI AND/OR BIFIDOBACTERIA WITH A NON-TRANSFERABLE ANTIBIOTIC RESISTANCE, HAVING THE SAME THERAPEUTIC INDICATION

USE OF ANTIBIOTICS WITH SPECIFIC THERAPEUTIC ACTIVITIES COMBINED WITH THE SIMULTANEOUS USE OF LACTOBACILLI AND/OR BIFIDOBACTERIA WITH A NON-TRANSFERABLE ANTIBIOTIC RESISTANCE, HAVING THE SAME THERAPEUTIC INDICATION

机译:使用具有特定治疗活性的抗生素,同时使用具有不可转移抗药性的乳酸杆菌和/或双歧杆菌,具有相同的治疗指征

摘要

The present invention relates to the use of antibiotics with specific therapeutic activities combined with the simultaneous use of lactobacilli and/or bifidobacteria having a non-transferable antibiotic resistance and with the same therapeutic indication as said antibiotics. In particular, the present invention relates to a composition comprising or, alternatively, consisting of antibiotics suitable for the treatment of acute and chronic intestinal infections due to gram-positive and gram-negative bacteria; diarrheic syndromes; diarrhea due to an imbalance of the intestinal microflora such as for example, summer diarrhea, traveler's diarrhea and enterocolitis; pre- and postoperative prophylaxis of infectious complications in gastrointestinal surgery; gastrointestinal diseases such as irritable bowel syndrome (IBS), constipation, alterations of intestinal microflora; chronic inflammatory intestinal diseases (IBD) and inflammations due to Helicobacter pylori; said antibiotics belonging to the rifamycin family, preferably rifaximin, being combined with specific strains of bacteria belonging to the species Bifidobacterium longum having the same therapeutic indication as said antibiotics.
机译:具有特定治疗活性的抗生素的使用本发明涉及具有特定治疗活性的抗生素的使用,同时使用具有不可转移的抗生素抗性并且具有与所述抗生素相同的治疗适应症的乳杆菌和/或双歧杆菌。特别地,本发明涉及一种组合物,其包含适合于治疗由革兰氏阳性和革兰氏阴性细菌引起的急性和慢性肠感染的抗生素或由其组成。腹泻综合征;由于肠道菌群失调引起的腹泻,例如夏季腹泻,旅行者腹泻和小肠结肠炎;胃肠道手术前后感染性并发症的预防肠胃疾病,如肠易激综合症(IBS),便秘,肠道菌群改变;慢性炎症性肠道疾病(IBD)和幽门螺杆菌引起的炎症;所述属于利福霉素家族的抗生素,优选利福昔明,与具有与所述抗生素相同的治疗适应症的长双歧杆菌种的特定细菌菌株组合。

著录项

  • 公开/公告号EP3288554A1

    专利类型

  • 公开/公告日2018-03-07

    原文格式PDF

  • 申请/专利权人 PROBIOTICAL S.P.A.;

    申请/专利号EP20160730891

  • 发明设计人 MOGNA GIOVANNI;

    申请日2016-04-29

  • 分类号A61K31/395;A61K31/496;A61K35/745;A61K35/747;A61P1;A61P1/12;

  • 国家 EP

  • 入库时间 2022-08-21 13:14:56

相似文献

  • 专利
  • 外文文献
  • 中文文献
获取专利

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号