PEPTIDES FOR USE IN TOPICAL TREATMENT OF RETINAL NEURODEGENERATIVE DISEASES, IN PARTICULAR EARLY DIABETIC RETINOPATHY AND OTHER RETINAL DISEASES WHERE NEURODEGENERATION PLAYS AN ESSENTIAL ROLE

摘要

PROBLEM TO BE SOLVED: To provide a tool useful for topically applying peptides and analogs of said peptides to the eye.SOLUTION: A peptide for use in local eye treatment and/or prevention of retinal neurodegenerative diseases, has a sequence length of 13 to 50 amino acids that can reach the retina, in which the N-terminal region of the peptide comprises the sequence: HXaaEGTFTSDXaaSXaaXaa, where Xaais an amino acid selected from alanine and glycine, Xaais an amino acid selected from valine and leucine, Xaais an amino acid selected from serine and lysine, Xaais an amino acid selected from tyrosine and glutamine and the N-terminal residue is a histidine.SELECTED DRAWING: None