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DETECTION OF CHROMOSOMAL ABNORMALITIES ASSOCIATED WITH PROGNOSIS OF NON-SMALL CELL LUNG CANCER

机译:非小细胞肺癌预后相关的染色体异常的检测

摘要

PROBLEM TO BE SOLVED: To provide a diagnostic method that can be provided to patients with early stage lung cancer, especially non-small cell lung cancer (NSCLC), to determine whether the patients are at increased risk of poor disease outcomes.SOLUTION: There is provided a method of determining a gain or loss in chromosome regions by a hybridization pattern showing at least one gain or loss by detecting hybridization including contacting a sample with one or more probes for one or more chromosome regions selected from the group consisting of 1p, 2q, 3q, 3q, 4p, 4q, 5q, 6p, 6q, 8p, 9p, 10q, 11q, 12p, 14q, 16q, 17q, and 19q.SELECTED DRAWING: None
机译:要解决的问题:提供一种诊断方法,可为患有早期肺癌,尤其是非小细胞肺癌(NSCLC)的患者提供一种确定患者是否患不良疾病结果的风险增加的解决方法。本发明提供了一种通过杂交模式来确定染色体区域中增益或损失的方法,该杂交模式通过检测杂交来显示至少一个增益或损失,包括使样品与一种或多种探针接触一个或多个选自1p的染色体区域的探针, 2q,3q,3q,4p,4q,5q,6p,6q,8p,9p,10q,11q,12p,14q,16q,17q和19q。

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