IGFBP7 for predicting AKI risk when measured before surgery

摘要

The present invention relates to a method for predicting the risk that a patient will suffer acute kidney injury (AKI) during or after surgery or after administration of a contrast agent. The method is based on the measurement of the level of the biomarker IGFBP7 (insulin-like growth factor binding protein 7) in a body fluid sample obtained from a patient prior to the surgical procedure or prior to the administration of a contrast agent. Furthermore, the present invention predicts the risk of patients suffering from acute kidney injury (AKI) based on the measurement of the biomarkers IGFBP7 (insulin-like growth factor binding protein 7) and cystatin C in body fluid samples obtained from patients On how to do. The present invention further includes kits and devices adapted to perform the methods of the present invention.