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Method for treating a patient according to vaccination with eculizumab or eculizumab variant

机译:根据依库丽单抗或依库丽单抗变体的疫苗接种治疗患者的方法

摘要

The disclosure provides inter alia C5 inhibition comprising administering an effective amount of a C5 inhibitor, such as eculizumab or eculizumab variant, to a patient who will be followed or will be vaccinated with a Neisseria meningococcal type B specific vaccine A method of treating a patient in need of treatment with an agent, or a method for inhibiting the formation of terminal complement in a patient. A method of vaccinating a patient being treated with eculizumab or eculizumab variant, said method being 14 3 days before or after this eculizumab or eculizumab variant administration, wherein said eculizumab or eculizumab variant is administered for the first time A method comprising administering a Neisseria meningococcal type B specific vaccine prior to about 14 days after administration of the composition.
机译:本公开内容尤其提供了对C5的抑制,包括对将要跟随或将要接种B型脑膜炎球菌奈瑟氏球菌特异性疫苗的患者施用有效量的C5抑制剂,例如依库丽单抗或依库丽单抗变体。需要药物治疗或抑制患者终末补体形成的方法。一种给接受依库珠单抗或依库珠单抗变异体治疗的患者接种疫苗的方法,所述方法是在施用依库珠单抗或依库珠单抗变异体之前或之后14 3天,其中首次施用所述依库珠单抗或依库珠单抗变异体。所述方法包括给予脑膜炎双球菌型在施用该组合物后约14天之前接种B特异性疫苗。

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