Enterovirus 71 animal model

摘要

The present invention relates to enterovirus 71 (EV71), development of animal models, and screening of candidate anti-EV71 compounds. More specifically, the invention relates to an enterovirus 71 (EV71) strain that is adapted for rodent cell line infection, or a cloning-derived virus that contains a mutation in VP1 is an immunocompetent rodent. Relates to the discovery that it is possible to cause disease. [Selection] Figure 23