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Method for producing complex of shikonin compound and β-1,3-1,6-glucan

机译:紫草素化合物与β-1,3-1,6-葡聚糖复合物的制备方法

摘要

PROBLEM TO BE SOLVED: To provide a method for producing a complex of a shikonin-based compound and -1,3-1,6-glucan, which has practically sufficient dispersibility and solubility in water.SOLUTION: Provided is a method for producing a complex of a shikonin-based compound and -1,3-1,6-glucan comprising a step of mixing a shikonin-based compound (a), a basic compound (b) and -1,3-1,6-glucan (c) having a ratio of the -1,6 bond to the -1,3 bond of 50 to 100%. Also provided is a method for producing a complex of a shikonin-based compound and -1,3-1,6-glucan comprising a step of mixing the shikonin-based compound (a) and -1,3-1,6-glucan (c) having the ratio of the -1,6 bond to the -1,3 bond of 50 to 100% in a solution made basic using the basic compound (b) and a step of neutralizing the solution using a neutralizer (d). The basic compound (b) preferably includes amines.
机译:解决的问题:提供一种制备紫草素类化合物和-1,3-1,6-葡聚糖的复合物的方法,该复合物在水中具有实际上足够的分散性和溶解性。紫草素类化合物与-1,3-1,6-葡聚糖的复合物,包括将紫草素类化合物(a),碱性化合物(b)和-1,3-1,6-葡聚糖( c)-1,6键与-1,3键的比率为50至100%。还提供了一种制备紫草素类化合物和-1,3-1,6-葡聚糖的复合物的方法,该方法包括将紫草素类化合物(a)和-1,3-1,6-葡聚糖混合的步骤。 (c)在使用碱性化合物(b)制成碱性的溶液中,具有-1,6键与-1,3键的比率为50至100%,以及使用中和剂(d)中和溶液的步骤。碱性化合物(b)优选包括胺。

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