Screening method for angiogenesis inhibitor targeting methylation of HIF-1α

摘要

The present application discloses a method for screening an angiogenesis inhibitor that targets the interaction between HIF1-α protein and SET7 / 9 methyltransferase or LSD1 demethylase, and the substance screened by the method according to the present application is a retinopathy or anticancer agent It can be usefully developed as a therapeutic agent for various diseases that require angiogenesis suppression such as. [Selection] Figure 7