Screening method for angiogenesis inhibitor targeting methylation of HIF-1α

摘要

The present application discloses a method of screening an angiogenesis inhibitor targeting the interaction between HIF 1- protein and SET 7/9 methyltransferase or LSD 1 demethylase, and the substances screened by the method according to the present application are retinopathy or anticancer drug Can be usefully developed as a therapeutic agent for various diseases requiring suppression of angiogenesis such as,(FIG.