Clonidine and / or clonidine derivatives for use in the prevention and / or treatment of adverse side effects of chemotherapy

摘要

The present invention relates to certain clonidine and / or clonidine derivatives for use in the prevention and / or treatment of deleterious side effects of alkylating agent chemotherapy other than those caused by mucosal inflammation. The present invention relates to clonidine and / or clonidine derivatives for the manufacture of a pharmaceutical composition intended to prevent and / or reduce the harmful side effects of alkylating agent chemotherapy other than those caused by mucosal inflammation. Also related to the use of. The present invention provides a kit comprising (a) clonidine and / or a clonidine derivative and (b) at least one alkylating chemotherapeutic agent as a combined preparation for simultaneous, separate or sequential use in the treatment of cancer. Is further targeted.