Pharmaceutical composition for external use containing luliconazole

摘要

PROBLEM TO BE SOLVED: To provide a coloration-inhibiting agent which inhibits the chronological coloration of a medicinal composition for external use which contains luliconazole and/or a pharmaceutically acceptable salt thereof; a method for inhibiting coloration; a histamine release inhibitor which contains luliconazole and/or a pharmaceutically acceptable salt thereof; and an antipruritic medicinal composition for external use which contains the same.SOLUTION: A medicinal composition for external use is prepared, the composition containing (A) luliconazole and/or a pharmaceutically acceptable salt thereof and (B) one or more substances selected from the group consisting of an antihistamine, a local anesthetic, a refrigerant, an anti-inflammatory agent, vitamins, a pH adjuster and a germicide. The composition thus prepared is free from chronological coloration due to luliconazole and/or a pharmaceutically acceptable salt thereof. In addition, the composition has an antifungal action and a histamine release-inhibiting action.