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Reduction of immunoassay interference and chaperone-chaperone fusion polypeptide for stabilization

机译:减少免疫测定干扰和伴侣-伴侣融合多肽的稳定作用

摘要

The invention concerns a fusion polypeptide comprising several molecules of folding helper polypeptides, comprising one multimerization domain, in particular Skp, and at least one molecule of SlyD or S1pA, wherein no further target polypeptide sequences are fused to said fusion polypeptide. The invention further concerns an immunoassay and the use of said fusion polypeptide in an immunoassay for reduction of interferences or minimizing false positive results or for stabilizing proteinaceous assay reagents. Further the invention concerns a reagent kit for use in an immunoassay comprising said fusion polypeptide.
机译:本发明涉及一种融合多肽,其包含几个折叠辅助多肽分子,包括一个多聚化结构域,特别是Skp,和至少一个SlyD或S1pA分子,其中没有其他靶多肽序列与所述融合多肽融合。本发明进一步涉及免疫测定以及所述融合多肽在免疫测定中的用途,其用于减少干扰或最小化假阳性结果或用于稳定蛋白质测定试剂。本发明进一步涉及用于免疫测定的试剂盒,其包含所述融合多肽。

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