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Compositions and methods for detection of drug resistant Mycobacterium tuberculosis

机译：耐药性结核分枝杆菌的组成和检测方法

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Methods for the rapid detection of the presence or absence of Mycobacterium tuberculosis (MTB) resistant to rifampicin (MTB-RIF) and/or MTB resistant to isoniazid (MTB-INH) in a biological or non-biological sample are described. The methods can include performing an amplifying step, a hybridizing step, and a detecting step. Furthermore, primers, probes targeting the genes for rpoB, inhA, and katG, along with kits are provided that are designed for the detection of MTB-RIF and/or MTB-INH. 展开▼

机译：快速检测在生物或非生物学中对利福平（MTB-RIF）和/或对异烟肼（MTB-INH）耐药的MTB（I）结核分枝杆菌（I）的存在或不存在的方法描述了样本。该方法可以包括执行扩增步骤，杂交步骤和检测步骤。此外，提供了针对rpoB，inhA和katG基因的引物，探针以及试剂盒，这些试剂盒被设计用于检测MTB-RIF和/或MTB-INH。展开▼

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公开/公告号US10087490B2

专利类型

公开/公告日2018-10-02

原文格式PDF

申请/专利权人 ROCHE MOLECULAR SYSTEMS INC.;
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申请/专利号US201414575879

发明设计人 JENNY A. JOHNSON;ROCHAK MEHTA;ANDY YUEN;
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申请日2014-12-18

分类号C12Q1/68;C12P19/34;C12Q1/689;

国家 US

入库时间 2022-08-21 13:05:09

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机译：用于检测耐药性结核分枝杆菌的培养基组合物，并通过使用该试剂盒检测毒性结核分枝杆菌的试剂盒

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机译：用于检测结核分枝杆菌，非结核分枝杆菌和结核分枝杆菌耐药的探针，芯片，试剂盒和方法

5. Medium composition for detecting drug resistant mycobacterium tuberculosis and kit for detecting drug resistant mycobacterium using it [P] . KR102274809B1 . 2021-07-08

机译：用于检测耐药性结核分枝杆菌和试剂盒的培养基组合物，用于检测耐药性分枝杆菌

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